The woman was told by a folk healer that her condition may have been caused by a curse. In , a woman reported that her breasts grew at puberty from nothing to a C cup in one month. The underlying cause of the rapidly growing breast connective tissue, resulting in gigantic proportions, has not been well-elucidated. They also commonly require the patient to try alternative treatments like physical therapy for a year or more. She underwent a bilateral reduction mammoplasty. Hypertrophy of the breast tissues may be caused by increased histologic sensitivity to certain hormones such as female sex hormones , prolactin , and growth factors.
A more severe case of virginal breast hypertrophy of an year-old girl was reported in
There are case reports of gigantomastia occurring in infants as well. She was administered tamoxifen afterward to suppress breast regrowth. Case Reports in Obstetrics and Gynecology. In some instances after aggressive or surgical treatment, the breast may continue to grow or re-grow, a complete mastectomy may be recommended as a last resort.